[1] Anderson GD, Elmer GW, Kantor ED, Templeton IE, Vitiello MV. Pharmacokinetics of valerenic acid after administration of valerian in healthy subjects. Phytother Res. 2005;19(9):801-803. doi:10.1002/ptr.1742
[2] Maier-Salamon A, Trauner G, Hiltscher R, Reznicek G, Kopp B, Thalhammer T, Jäger W. Hepatic metabolism and biliary excretion of valerenic acid in isolated perfused rat livers: role of Mrp2 (Abcc2). J Pharm Sci. 2009;98(10):3839-3849. doi:10.1002/jps.21671
[3] Torchilin VP. Recent advances with liposomes as pharmaceutical carriers. Nat Rev Drug Discov. 2005;4(2):145-160. doi:10.1038/nrd1632
[4] Carr AC. Do Liposomal Vitamin C Formulations Have Improved Bioavailability? A Scoping Review Identifying Future Research Directions. Basic Clin Pharmacol Toxicol. 2025;137(1):e70067. doi:10.1111/bcpt.70067
[5] Miljanović A, et al. Spray-dried microencapsulation of plant extracts: encapsulation efficiency 95.9-98.0% with gastric protection and targeted intestinal release. Foods. 2025;14(4):620. doi:10.3390/foods14040620
[6] Pasha SI, Meraj A, Meraj A, Mohammed A, Tanzil A, Fatima A, Koneru A. Preparation and In vitro Characterization of Valerianic Acid Loaded Polymeric Nanoparticles. Biosci Biotech Res Asia. 2023;20(1):127-134.
[7] Khom S, Baburin I, Timin E, Hohaus A, Trauner G, Kopp B, Hering S. Valerenic acid potentiates and inhibits GABA(A) receptors: molecular mechanism and subunit specificity. Neuropharmacology. 2007;53(1):178-187. doi:10.1016/j.neuropharm.2007.04.018
[8] Shinjyo N, Waddell G, Green J. Valerian Root in Treating Sleep Problems and Associated Disorders — A Systematic Review and Meta-Analysis. J Evid Based Integr Med. 2020;25:2515690X20967323. doi:10.1177/2515690X20967323
[9] European Medicines Agency, Committee on Herbal Medicinal Products (HMPC). European Union herbal monograph on Valeriana officinalis L., radix. EMA/HMPC.
[10] Azizi H, Shojaii A, Hashem-Dabaghian F, Noras M, Boroumand A, Ebadolahzadeh Haghani B, Ghods R. Effects of Valeriana officinalis (Valerian) on tension-type headache: a randomized, placebo-controlled, double-blind clinical trial. Avicenna J Phytomed. 2020;10(3):297-304. doi:10.22038/ajp.2019.14211
[11] Rahim MA, Zahran HA, Jaffar HM, Ambreen S, Ramadan MF, Al-Asmari F, Castro-Muñoz R, Zongo E. Liposomal Encapsulation in Food Systems: A Review of Formulation, Processing, and Applications. Food Sci Nutr. 2025;13(8):e70587. doi:10.1002/fsn3.70587.










